Table 2.
Homotypic adhering junctions: results of immunolocalization experiments (summary for all species examined)
| Molecule | Sertoli–Sertoli and Sertoli–Spermatogonia cell junctions | Excurrent duct epithelia |
|---|---|---|
| Transmembrane glycoproteins (Cadherins) | ||
| E-cadherin | − | + |
| VE-cadherin | − | − |
| N-cadherin | + | − |
| P-cadherin | − | − |
| Cadherin-11 | − | − |
| Desmoglein 1 (Dsg-1) | − | − |
| Desmoglein 2 (Dsg-2) | − | + |
| Desmoglein 3 (Dsg-3) | − | − |
| Desmocollin 1 (Dsc-1) | − | − |
| Desmocollin 2 (Dsc-2) | − | + |
| Desmocollin 3 (Dsc-3) | − | − |
| Other transmembrane molecules | ||
| EpCAM | − | + |
| Protein PERP | − | + |
| Cytoplasmic plaque proteins | ||
| Desmoplakin I+II | − | + |
| Plakophilin 1 | − | − |
| Plakophilin 2 | − | + |
| Plakophilin 3 | − | + |
| β-Catenin | + | + |
| Protein p120 | + | + |
| Protein p0071 | + | + |
| Plakoglobin | + | + |
| Neurojungin | − | − |
| α-Catenin | + | + |
| Protein ZO-1 | (+/−)a | + |
| Myozap | (+/−)a | + |
| Striatinb | + | + |
| Protein LUMA | – | + |
aFor unexplained reasons, we have consistently found reactions of the plaque proteins myozap and ZO-1 in adherens junctions of Sertoli cells in the rodent testes but not in the other species examined in which only the adherens junctions of the endothelial and some interstitial mesenchymal cells showed myozap- and/or ZO-1-positive junctions
bWhether it is striatin or a closely related member of the striatin family of proteins is not yet clear