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. Author manuscript; available in PMC: 2014 Aug 29.
Published in final edited form as: Biomaterials. 2009 Dec 21;31(9):2665–2672. doi: 10.1016/j.biomaterials.2009.12.005

Figure 1. Addition of CMC increases gene transfer to mouse nasal epithelium.

Figure 1

Figure 1

Figure 1

Mouse nasal epithelium was perfused with pCIKlux (80 μg/mouse) or pCIKempty (negative control) complexed to GL67A or remained untransfected (UT) (perfusion rate: 7 μl/min). Viscoelastic gels to final concentrations ranging from 0.25% to 1% were added to the lipid/DNA complexes (final volume 150 μl/mouse). 24 hr after transfection luciferase expression was quantified in tissue homogenate. (A and B) carboxymethylcellulose (CMC), (C) methylcellulose (MC). Bars represent group mean ±SEM (n=8/group). *=p<0.05 compared to 0% CMC.