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Nasal potential difference measurements in CF knockout mice transfected with CFTR-expression plasmids complexed to the cationic lipid GL67
| Plasmid | Baseline (absolute PD) | Amiloride (ΔPD) | Low Chloride (ΔPD) | n |
|---|---|---|---|---|
| pCIKCFTR | −14.65 (1.33) | 10.80 (1.08) | −0.48 (0.38) | 31 |
| pCIKGFP-CFTR | −15.11 (1.31) | 8.84 (1.33) | −0.49 (0.37) | 30 |
| pCI-empty | −15.99 (1.41) | 11.61 (1.35) | −0.47 (0.52) | 29 |
Numbers indicate group mean (SEM). For reference non-CF low chloride responses are 9.5±3.5 mV.
