Table 1.
Titers of neutralizing antibodies (nAbs) raised in guinea pigs.
| Guinea pig groups (n = 6) |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 1, 3, 7, 8 | 2, 4, 5, 6, 9 | Control | |
| AHSV 1 | 112 | 11 | ||||||||||
| (48–176) | (2–19) | |||||||||||
| AHSV 2 | 37 | 10 | ||||||||||
| (27–48) | (1–19) | |||||||||||
| AHSV 3 | 341 | 19 | ||||||||||
| (236–447) | (11–28) | |||||||||||
| AHSV 4 | 171 | 12 | ||||||||||
| (118–224) | (9–16) | |||||||||||
| AHSV 5 | 179 | 53 | ||||||||||
| (14–345) | (40–67) | |||||||||||
| AHSV 6 | 1365 | 12 | 117 | |||||||||
| (942–1788) | (3–21) | (58–177) | ||||||||||
| AHSV 7 | 8 | 122 | 20 | |||||||||
| (3–13) | (46–197) | (12–28) | ||||||||||
| AHSV 8 | 3 | 96 | 4 | 2 | ||||||||
| (1 –4) | (10–87) | (2–7) | (0–4) | |||||||||
| AHSV 9 | 24 | 853 | 19 | |||||||||
| (17–31) | (642–1065) | (10–27) | ||||||||||
Single VP2 proteins (1–9) or with cocktails of 4 or 5 different VP2 proteins (1, 3, 7, 8 or 2, 4, 5, 6, 9, respectively) were used to immunize six guinea pigs per group. Titers of nAbs against each of the AHSV serotypes (AHSV-1–AHSV-9) were determined. The average nAb titers were calculated and the 95% confidence interval is indicated between brackets. Titers of nAbs <2 were evaluated as 0.