Table 4.
Isotype switching in abnormal bacteriophage patients.
| Parameter | Low total antibody and abnormal isotype switching (38/75) | Made 0% IgG (24/38) | Low total antibody but able to switch to IgG (36/75) | Normal total antibody but abnormal isotype switching (1/75) | Number on Ig replacement |
|---|---|---|---|---|---|
| ABNORMAL BACTERIOPHAGE ΦX 174 N = 75 | |||||
| IgG <300 | 12 | 8/12 | 18 | 1 | 0/31 |
| IgG 300–499 | 12 | 7/12 | 12 | 0 | 3/24 |
| IgG 500–699 | 7 | 3/7 | 2 | 0 | 2/9 |
| IgG >700 | 6 | 5/6 | 4 | 0 | 6/10 |
| IgG not available | 1 | 1/1 | 0 | 0 | 0/1 |
Isotype switching. Breakdown of the 75 patients with abnormal bacteriophage results describing defect in antibody production, isotype switching, or both.