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In vivo validation of Cybb in rotenone toxicity using the treadmill exhaustion test. Two inbred mouse strains were tested for distance traveled during a 3.5 h time span in the stress treadmill test. The mice treated with vehicle (n = 6 per strain) showed similar distances for the two strains; however, FVB/NJ mice treated with rotenone (n = 6) had a larger performance decrease than BTBR T+ tf/J mice (n = 6) *p < 0.05. Data are expressed as means ± SE.
