Table 4.
Overview of Infectious Keratitis after LASIK
| Study | Year | Total eyes |
Total Infections (eyes) |
Incidence | # Culture positive |
Primary Organism |
Final CDVA > 20/20 |
Final CDVA > 20/40 |
|---|---|---|---|---|---|---|---|---|
| Karp5 | 2003 | N/A | 15 | N/A | 15 |
Mycobacterium (6) S. aureus (4) Pseudomonas (1) Fungal (3) Acanthamoeba (1) |
5/15 (33%) | 10/15(66%) NLP: 2 (13%) |
| Freitis4 | 2003 | N/A | 10 | N/A | N/A | Mycobacterium (10) | 0 (0%) | 4 (40%) |
| Solomon8 | 2003 | 338,500* | 116 | 0.03%* | 46/69 (66%) |
Mycobacterium (33) Staph sp. (23) Strep sp. (2) Gram negative (2) Fungal (7) Nocardia (2) |
^37/69 (53%) | ^58 (84%) |
| Moshifar7 | 2007 | 10,477 | 33 | 0.31% | 23 cases (viral) 10/33 cases (bacterial) |
Adenovirus (18) HSV (5) Mycobacterium (4) Staph sp. (3) Pseudomonas (1) Polymicrobial (2) |
20/33 (59%) | 26/33 (77%) |
| Solomon9 | 2007 | N/A | 10 (LASIK) | N/A | N/A | MRSA (100%) | 1 (10%) | 8 (80%) |
| Llovet6 | 2010 | 204,586 | 72 | 0.035% | 21/54 (39%) |
S. epidermidis (9) S. pneumoniae (8) S. viridans (2) S. pyogenes (1) S. aureus (1) |
38/72 (53%) | 67/72 (93%) |
| Garg10 | 2010 | N/A | 17 | N/A | N/A | Nocardia (5) Mycobacterium (4) Fungal (4) Acanthamoeba (2) Corynebacterium (1) S. epidermidis (1) |
1 (6%) | 4 (24%) CF or worse: 8 (47%) |
| Yamaguchi11 | 2011 | N/A | 39 | N/A | 11/30 (36%) |
Mycobacterium (9) Corynebacterium (1) Gram + (1) |
22 (56%) | 33 (85%) |
*
: the total number of cases in So lomon et al. was estimated based on survey responses
^
: %20/20 and 20/40 were derived from culture-positive cases only