Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Aug 29;8:266. doi: 10.3389/fnins.2014.00266

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Norcini, Sideris, Martin Hernandez, Zhang, Blanck and Recio-Pinto.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Predicted mRNA targets for the identified miRs. TargetScan and Miranda software was used to identify potential mRNA targets for the identified miRs. The list of potential mRNA targets was filtered: by selecting those that encode for ion channels. Here we show those encoding for voltage-dependent sodium channels: α (SCNXA) and β (SCNXB) subunits; voltage-dependent calcium channels: α (CACNA1X), β (CaCh-β X), γ (CaCh- γX), γ2δX (CaCh-γ2δX), and δ (CaCh-δX) subunits. The pacemaker channels (HCNX), the ligand-gated, non-selective cation channel TRPV1, the transient receptor potential channel TRPM8, and cannabinoid receptors (CNRX). “X” Stands for various numbers as indicated in the figure. We then used the http://www.jbldesign.com/jmogil/enter.html (Lacroix-Fralish et al., 2007) to find which mRNA targets have been associated with neuronal hypersensitivity by using knockout studies.