TABLE 2.
Genes most highly induced by the AAR regardless of mechanism
The 15 genes most highly induced by the AAR regardless of mechanism are shown. The expression microarray data are from HepG2 cells incubated for 8 h in DMEM ± histidine with or without 2.5 μm PD98059.
| Probe set ID | Gene symbol | p value (−His/DMEM) | Fold change (−His/DMEM) |
|---|---|---|---|
| PSR05009822.hg.1 | EGR1 | 2.50E-13 | 23.8496 |
| JUC14003021.hg.1 | FOS | 2.37E-07 | 11.7154 |
| PSR01016127.hg.1 | SLC22A15 | 4.94E-08 | 10.7615 |
| PSR05001385.hg.1 | SUB1 | 1.92E-10 | 9.99431 |
| JUC06005364.hg.1 | NCOA7 | 6.34E-08 | 9.89601 |
| JUC04002867.hg.1 | EREG | 2.39E-08 | 9.82107 |
| PSR01027796.hg.1 | ATF3 | 1.13E-10 | 9.71156 |
| JUC09000186.hg.1 | VLDLR | 5.11E-08 | 9.60593 |
| JUC19005801.hg.1 | PPP1R15A | 1.28E-12 | 9.24786 |
| PSR12006935.hg.1 | SHMT2 | 1.69E-16 | 8.12226 |
| PSR15003833.hg.1 | TMOD2 | 2.01E-09 | 7.07384 |
| PSR12006973.hg.1 | INHBE | 5.90E-12 | 7.0701 |
| JUC07012293.hg.1 | ASNS | 1.32E-07 | 6.78668 |
| JUC01023344.hg.1 | ZZZ3 | 1.46E-06 | 6.78157 |
| JUC01003020.hg.1 | SESN2 | 1.33E-10 | 6.72953 |