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. 2014 Jul 15;289(35):24665–24679. doi: 10.1074/jbc.M114.565028

TABLE 3.

AAR-induced Genes with the Greatest Degree of MEK Dependence

The 15 AAR-induced genes with the greatest degree of MEK dependence are shown. The expression microarray data are from HepG2 cells incubated for 8 h in DMEM ± histidine with or without 2.5 μm PD98059.

Probe set ID Gene symbol Fold change (−His/DMEM) p value (−His/DMEM) Percentage of MEK dependence
JUC14003021.hg.1 FOS 11.7154 2.37E-07 88.6184
PSR05009822.hg.1 EGR1 23.8496 2.50E-13 88.3077
PSR04005637.hg.1 IL8 5.50397 9.82E-08 86.2509
PSR10009587.hg.1 DUSP5 2.44081 1.12E-09 82.6263
PSR07004534.hg.1 IGFBP1 2.11808 7.68E-05 80.4794
JUC02011397.hg.1 CCL20 2.73831 6.44E-10 80.0432
JUC18005299.hg.1 SERPINB8 2.29491 0.00177338 79.9067
PSR09013309.hg.1 AQP3 3.58114 3.36E-08 78.3926
PSR22011280.hg.1 LIF 3.97938 2.96E-11 77.2063
JUC01008446.hg.1 MAB21L3 3.2181 1.47E-09 76.3792
JUC03014269.hg.1 FILIP1L 2.22555 0.00718454 75.6935
PSR05025990.hg.1 SPRY4 3.24396 2.34E-09 75.0695
JUC08008916.hg.1 HEY1 3.2598 1.08E-08 75.0352
JUC04002867.hg.1 EREG 9.82107 2.39E-08 74.9477
JUC06000413.hg.1 EDN1 2.84431 4.59E-06 74.6727