Table 4.

Percentage of mice showing IHC staining in particular locations in the wall of the GI tract

		epithelium			lamina propria				submucosa
Genotype	Status - % fat in diet (n)	basolateral surface	paracellular junctions	effacing lesion	between cells	within all cell types	within PMNs	within MP/DC	within connective tissue	within all cell types	within PMNs	within MP/DC	associated with vascular tissue	associated with lymphoid tissue	associated with histiocytes
Experiment 1
C57BL/6 IL-10−/−	control - 11% (10)	10	10	10	10	10	10	10	10	10	10	10	10	10	10
	infected - 11% (10)	50	60	50	20	50	20	40	0	40	0	20	0	30	10
	infected - 6% (10)	50	50	60	40	50	30	40	10	40	10	30	10	10	50
C57BL/6 IL-10+/+	infected - 11% (10)	0	0	0	0	10	0	10	0	20	10	20	0	0	0
C3Bir IL-10−/−	infected - 11% (10)	60	60	60	30	60	20	30	0	60	10	20	20	20	20
C3H IL-10+/+	infected - 11% (10)	20	20	30	0	50	0	20	0	40	0	30	0	0	0
NOD IL-10−/−	infected - 6% (10)	60	60	60	20	80	20	40	0	70	0	10	30	40	40
NOD IL-10+/+	infected - 6% (10)	20	30	40	0	20	0	0	0	20	0	0	0	0	0
Experiment 2
C3Bir IL-10−/−	control - 11% (5)	80	80	80	20	20	20	20	0	40	20	40	20	0	0
	infected - 11% (13)	61	69	77	23	54	23	54	15	77	8	77	31	31	15
C3H IL-10+/+	control - 11% (6)	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	infected - 11% (12)	33	33	33	8	8	8	8	0	17	8	17	8	0	0
Experiment 3
NOD IL-10−/−	control - 6% (2)	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	infected - 6% (3)	67	67	67	67	67	0	67	0	33	0	33	33	33	0
NOD IL-10+/−	control - 6% (2)	0	0	0	0	0	0	0	0	0	0	0	0	0	0
	infected - 6% (4)	25	25	25	0	25	0	25	0	0	0	0	0	0	0
NOD IL-10+/+	control - 6% (7)	0	0	0	0	43	0	43	0	14	0	14	0	0	0
	infected - 6% (18)	67	67	44	5	78	0	78	0	28	0	28	0	5	0