Table 2.
Muscarinic Receptor Subtype |
Ocular Tissue |
||
Ciliary Muscle |
Iris |
Retina |
|
M1 | ++ | ++ | + |
PRL, OPL, IPL | |||
M2 | ++ | + | ++ |
PRL, OPL, NFL | |||
M3 | +++ | +++ | ++ |
IPL, OPL, NFL | |||
M4 | ++ | ++ | + |
IPL, OPL, NFL | |||
M5 | +++ | + | + |
OPL, IPL | |||
+++ | |||
NFL |
Distribution of staining in the retina is shown. PRL, photoreceptor layer; NFL, nerve fiber layer; +++, highest specific staining; +, lowest specific staining.