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. 2014 Aug 20;14:604. doi: 10.1186/1471-2407-14-604

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© Derr et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of LSD1, HDAC2 and SIRT1 in different tumor stages. We included 182 patients with a stage I disease, 227 patients with a stage II disease and 51 patients with a stage III tumor. (A) Boxplot showing the percentage of positive tumor cells for LSD1 versus the TNM tumor stage (I-III) at moment of diagnosis. (B) HDAC2 expression levels versus TNM tumor stage shown in a boxplot. (C) The expression levels of SIRT1 versus TNM tumor stage represented in a boxplot. The thick horizontal lines represent the mean percentage of positive tumor cells in each category. Outliers are represented by circles. The p-values were calculated using the one-way ANOVA method and p-values ≤0.05 are considered as significant.