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. 2014 Mar 15;9(3):632–645. doi: 10.4056/sigs.4998989

Table 4. Number of genes associated with the 25 general COG functional categories.

Code       Value        %agea         Description
J       158        5.6         Translation
A       0        0         RNA processing and modification
K       159        5.7         Transcription
L       104        3.7         Replication, recombination and repair
B       3        0.1         Chromatin structure and dynamics
D       24        0.9         Cell cycle control, mitosis and meiosis
Y       0        0         Nuclear structure
V       22        0.8         Defense mechanisms
T       74        2.6         Signal transduction mechanisms
M       133        4.7         Cell wall/membrane biogenesis
N       40        1.4         Cell motility
Z       0        0         Cytoskeleton
W       0        0         Extracellular structures
U       38        1.4         Intracellular trafficking and secretion
O       118        4.2         Posttranslational modification, protein turnover, chaperones
C       196        7.0         Energy production and conversion
G       165        5.9         Carbohydrate transport and metabolism
E       334        11.9         Amino acid transport and metabolism
F       73        2.6         Nucleotide transport and metabolism
H       157        5.6         Coenzyme transport and metabolism
I       154        5.5         Lipid transport and metabolism
P       112        4.0         Inorganic ion transport and metabolism
Q       123        4.4         Secondary metabolites biosynthesis, transport and catabolism
R       379        13.5         General function prediction only
S       238        8.5         Function unknown
-       714        22.06         Not in COGs

a) The total is based on the total number of protein coding genes in the annotated genome.