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. 2013 Dec 31;9(3):495–504. doi: 10.4056/sigs.4708537

Table 4. Number of genes associated with general COGs functional categories.

Code    Value     % agea     Description
J    156     6.38     Translation, ribosomal structure, and biogenesis
A    4     0.16     RNA processing and modification
K    218     8.91     Transcription
L    167     6.83     Replication, recombination, and repair
B    1     0.04     Chromatin structure and dynamics
D    21     0.86     Cell cycle control, cell division, and chromosome partitioning
Y    0     0.00     Nuclear structure
V    40     1.64     Defense mechanisms
T    100     4.09     Signal transduction mechanisms
M    112     4.58     Cell wall/membrane/envelope biogenesis
N    0     0.00     Cell motility
Z    1     0.04     Cytoskeleton
W    0     0.00     Extracellular structures
U    32     1.31     Intracellular trafficking, secretion, and vesicular transport
O    69     2.82     Posttranslational modification, protein turnover, and chaperones
C    131     5.36     Energy production and conversion
G    129     5.27     Carbohydrate transport and metabolism
E    315     12.88     Amino acid transport and metabolism
F    74     3.03     Nucleotide transport and metabolism
H    101     4.13     Coenzyme transport and metabolism
I    81     3.31     Lipid transport and metabolism
P    154     6.30     Inorganic ion transport and metabolism
Q    51     2.09     Secondary metabolites biosynthesis, transport, and catabolism
R    307     12.55     General function prediction only
S    182     7.42     Function unknown
-    723     24.65     Not in COGs

aThe total is based on the total number of protein-coding genes in the annotated genome.