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. 2014 Mar 15;9(3):807–820. doi: 10.4056/sigs.5199182

Table 5. Number of genes associated with the 25 general COG functional categories.

Code      Value        % agea        Description
J      201        3.91        Translation, ribosomal structure and biogenesis
A      0        0        RNA processing and modification
K      483        9.39        Transcription
L      166        3.23        Replication, recombination and repair
B      1        0.02        Chromatin structure and dynamics
D      43        0.84        Cell cycle control, mitosis and meiosis
Y      0        0        Nuclear structure
V      119        2.31        Defense mechanisms
T      313        6.08        Signal transduction mechanisms
M      205        3.98        Cell wall/membrane biogenesis
N      73        1.42        Cell motility
Z      5        0.1        Cytoskeleton
W      0        0        Extracellular structures
U      50        0.97        Intracellular trafficking and secretion
O      121        2.35        Posttranslational modification, protein turnover, chaperones
C      180        3.5        Energy production and conversion
G      560        10.88        Carbohydrate transport and metabolism
E      355        6.9        Amino acid transport and metabolism
F      93        1.81        Nucleotide transport and metabolism
H      130        2.53        Coenzyme transport and metabolism
I      108        2.1        Lipid transport and metabolism
P      248        4.82        Inorganic ion transport and metabolism
Q      113        2.2        Secondary metabolites biosynthesis, transport and catabolism
R      648        12.59        General function prediction only
S      328        6.38        Function unknown
-      1,264        24.57        Not in COGs

a The total is based on the total number of protein-coding genes in the annotated genome