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. 2014 Apr 10;9(3):1198–1210. doi: 10.4056/sigs.5501035

Table 5. Number of genes associated with the 25 general COG functional categories.

Code       Value       %agea        Description
J       152       6.76        Translation
A       4       0.18        RNA processing and modification
K       174       7.74        Transcription
L       178       7.92        Replication, recombination and repair
B       4       0.18        Chromatin structure and dynamics
D       40       1.78        Cell cycle control, mitosis and meiosis
Y       0       0        Nuclear structure
V       92       4.09        Defense mechanisms
T       82       3.65        Signal transduction mechanisms
M       99       4.41        Cell wall/membrane biogenesis
N       14       0.62        Cell motility
Z       5       0.22        Cytoskeleton
W       0       0        Extracellular structures
U       51       2.27        Intracellular trafficking and secretion
O       78       3.48        Posttranslational modification, protein turnover, chaperones
C       130       5.78        Energy production and conversion
G       221       9.83        Carbohydrate transport and metabolism
E       125       5.56        Amino acid transport and metabolism
F       64       2.85        Nucleotide transport and metabolism
H       59       2.62        Coenzyme transport and metabolism
I       51       2.27        Lipid transport and metabolism
P       127       5.65        Inorganic ion transport and metabolism
Q       17       0.75        Secondary metabolites biosynthesis, transport and catabolism
R       238       10.6        General function prediction only
S       220       9.79        Function unknown
-       22       0.98        Not in COGs

a The percentage is based on the total number of protein coding genes in the annotated genome.