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. 2014 Mar 15;9(3):1031–1045. doi: 10.4056/sigs.5189179

Table 5. Number of genes associated with the 25 general COG functional categories.

Code        Value        %agea         Description
J        195        3.33         Translation
A        0        0         RNA processing and modification
K        570        9.73         Transcription
L        186        3.18         Replication, recombination and repair
B        1        0.02         Chromatin structure and dynamics
D        31        0.53         Cell cycle control, mitosis and meiosis
Y        0        0         Nuclear structure
V        101        1.72         Defense mechanisms
T        354        6.05         Signal transduction mechanisms
M        247        4.22         Cell wall/membrane biogenesis
N        76        1.30         Cell motility
Z        2        0.03         Cytoskeleton
W        1        0.02         Extracellular structures
U        59        1.01         Intracellular trafficking and secretion
O        127        2.17         Posttranslational modification, protein turnover, chaperones
C        189        3.23         Energy production and conversion
G        591        10.09         Carbohydrate transport and metabolism
E        414        7.07         Amino acid transport and metabolism
F        96        1.64         Nucleotide transport and metabolism
H        125        2.13         Coenzyme transport and metabolism
I        144        2.46         Lipid transport and metabolism
P        365        6.23         Inorganic ion transport and metabolism
Q        147        2.51         Secondary metabolites biosynthesis, transport and catabolism
R        735        12.55         General function prediction only
S        339        5.79         Function unknown
-        1,551        26.49         Not in COGs

a The total is based on the total number of protein coding genes in the annotated genome