Table 3.

Cox proportional hazard regression analysis of ANGPTL4 mRNA and clinicopathological parameters in relation to the overall and disease-free survivals of HCC patients after hepatectomy

	Univariable analysis		Multivariable analysis
	HR (95% CI)	P	HR (95% CI)	P
1. Overall survival
ANGPTL4 mRNA
Downregulation vs Non-downregulation	2.39(1.33-4.27)	0.003**	1.48(0.81-2.72)	0.204
pTNM staging
Advanced vs early	5.37(2.25-12.81)	0.000***	2.26(0.71-7.18)	0.168
Venous infiltration
Presence vs absence	4.41(2.25-8.67)	0.000***	2.11(0.88-5.09)	0.096
AFP level
>20 ng/ml vs ≤20 ng/ml	3.10(1.60-5.99)	0.001**	2.12(1.07-4.21)	0.031*
2. Disease-free survival
ANGPTL4 mRNA
Downregulation vs Non-downregulation	1.83(1.12-2.99)	0.017*	1.40(0.84-2.32)	0.201
pTNM staging
Advanced vs early	2.87(1.57-5.24)	0.001**	1.33(0.53-3.35)	0.544
Venous infiltration
Presence vs absence	3.14(1.84-5.37)	0.000***	2.36(1.06-5.26)	0.036*

Abbreviations: HR hazard ratio, CI confidence interval; *, p<0.05; **, p<0.01; ***, p<0.001.