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Test results of unrelated pairs vs. related pairs at different heteroplasmy levels
| Heteroplasmy level threshold |
P-value (Resampling Test*) |
P-value (Wilcoxon Rank Sum Test) |
|---|---|---|
| ≤100% | <0.0001 | 7.8 × 10−18 |
| ≤5% | <0.0001 | 1.0 × 10−12 |
| ≤1% | <0.0001 | 5.8 × 10−12 |
| ≤0.5% | <0.0001 | 2.1 × 10−11 |
| ≤0.25% | <0.0001 | 6.9 × 10−9 |
| ≤0.2% | 0.0001 | 1.7 × 10−7 |
| ≤0.15% | 0.0012 | 7.1 × 10−5 |
| ≤0.1% | 0.0119 | 0.09 |
The resampling test was performed for 10,000 iterations
