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. 2014 Aug 13;11:143. doi: 10.1186/s12974-014-0143-1

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© Heuss et al. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Phagocytosis of retinal ganglion cells (RGC) following an optic nerve injury (ONC). (A) Time course of RGC apoptosis following an ONC. (B) Analysis of DiI uptake in GFP^hi DC and GFP^lo MG/macrophages following an ONC. Retinas were labeled by injection of DiI into the superior colliculus. After 7 days the mice were given an ONC; retinas were harvested 7, 10, 13, and 17 days later. CD45⁺ cells were examined by flow cytometry as shown in Figure 4. All cells in (B) are CD11b⁺.