Table 3.

Trials targeting the VC/VS region

VC/VS
Reference	Responders (ratio)	Follow-up	Patients published elsewhere	Y-BOCS Reduction
Greenberg, 2006 [39]	4/8	36 months		35.5%
Greenberg, 2010* [40]	16/26	36 months	10 patients from Greenberg et al. [39], and five patients included in Nuttin et al. [23]	38.5%
Goodman, 2010* [41]	4/6	12 months	Five patients from Greenberg et al. [39]	91.3%
Tsai, 2012 [42]	2/4	15 months		53,4%
Mean	50%			41.5%

VC/VS: ventral capsule/ventral striatum. Responders’ ratio: responders defined as 35% improvement in Y-BOCS score or more. Follow-up: latest follow-up reported. Patients included elsewhere: Number of patients of which the data has been reported before and corresponding publication. Y-BOCS reduction: mean reduction for new patients at latest follow-up or reduction range if individual data not available. *Data not included in pooled means due to missing information/republisheded data.