Table 3.
Prevalence of polymorphic HML-2 proviruses in breast cancer
| HML-2 Locus | Breast cancer cases a | Healthy controls a | ||||
|---|---|---|---|---|---|---|
| # Positive | Frequency | # Positive | Frequency | χ 2 | p -value b | |
| 1p31.1 | 16 | 0.64 | 17 | 0.68 | 0.09 | 0.76 |
| 3q13.2 | 25 | 1.00 | 25 | 1.00 | ||
| 6q14.2 | 21 | 0.84 | 23 | 0.92 | 0.75 | 0.34 |
| 7p22.1R | 25 | 1.00 | 25 | 1.00 | ||
| 7p22.1 L | 24 | 0.96 | 25 | 1.00 | 1.02 | 0.31 |
| 8p23.1a | 6 | 0.24 | 1 | 0.04 | 4.15 | 0.04* |
| 10p12.1 | 24 | 0.96 | 25 | 1.00 | 1.02 | 0.31 |
| 11q22.1 | 23 | 0.92 | 20 | 0.80 | 1.49 | 0.22 |
| 12q13.2 | 20 | 0.80 | 21 | 0.84 | 0.13 | 0.72 |
| 12q14.1 | 23 | 0.92 | 22 | 0.88 | 0.22 | 0.67 |
| 19p12b | 3 | 0.12 | 3 | 0.12 | ||
aBand sizes are based on estimated fragment lengths; each has been indicated by arrow in Figure 2.
bTotal sample size was 50 (n = 25 per group).
*Indicates significance (p > 0.05) within the dataset (not corrected for multiple comparisons).