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. Author manuscript; available in PMC: 2014 Aug 29.
Published in final edited form as: AIDS. 2014 Feb 20;28(4):511–519. doi: 10.1097/QAD.0000000000000124

Table 2.

Factors associated with pulmonary artery systolic pressure at least 30 mmHg in HIV-infected participants.

Parameter Unadjusted Prevalence ratio (95% CI), P value Fully adjusted Prevalence ratio (95% CI), P value
ADMA (per 0.1 μmol/l increase) 1.19 (1.01, 1.42), P =0.043 1.13 (0.94, 1.35), P =0.20
Age (per decade) 1.11 (0.92, 1.33), P =0.28 1.13 (0.92, 1.38), P =0.25
Female vs. male 1.36 (0.90, 2.1), P =0.15 1.10 (0.68, 1.78), P =0.69
African–American vs. white 1.40 (0.96, 2.1), P =0.080 1.24 (0.80, 1.91), P =0.33
Other/Latino vs. white 1.24 (0.75, 2.0), P =0.40 1.23 (0.73, 2.1), P =0.44
IVDU (current vs. never) 1.85 (1.09, 3.1), P =0.022 1.48 (0.73, 3.0), P =0.28
IVDU (past vs. never) 1.33 (0.91, 1.96), P =0.15 1.31 (0.81, 2.1), P =0.27
Cigarette smoking (current vs. never) 1.39 (0.92, 2.1), P =0.11 1.06 (0.65, 1.73), P =0.80
Cigarette smoking (past vs. never) 1.04 (0.66, 1.64), P =0.87 0.99 (0.61, 1.62), P =0.98
Stimulant use (current vs. never) 1.36 (0.86, 2.1), P =0.19 0.97 (0.53, 1.80), P =0.93
Stimulant use (past vs. never) 0.99 (0.66, 1.47), P =0.95 0.77 (0.48, 1.24), P =0.28
hsCRP (per doubling) 1.05 (0.95, 1.15), P =0.32 1.01 (0.91, 1.12), P =0.91
D-dimer (per doubling) 1.14 (1.00, 1.30), P =0.044 1.04 (0.89, 1.22), P =0.60
IL-6 (per doubling) 1.19 (1.05, 1.34), P =0.0057 1.10 (0.95, 1.29), P =0.20

Analysis includes all 214 HIV-infected participants; prevalence of outcome was 59.8% (128 of 214 participants). Multiple imputation was used to handle missing covariates: CRP (N =181), D-dimer (N =170), and IL-6 (N =164). ADMA, asymmetric dimethylarginine; CI, confidence interval; IVDU, intravenous drug use; PASP, pulmonary artery systolic pressure; PR, prevalence ratio.