Table 3.
Participant characteristics, general health and antibiotics prescribed, by vaccination group
| |
PCV7 |
PHiD-CV1 |
Absolute difference in mean or % [95% CI] |
P* |
||
|---|---|---|---|---|---|---|
| N | Mean (SD) or% | N | Mean (SD) or% | |||
| Age (mo) |
444 |
20 (8) |
451 |
18 (7) |
2 [1-3] |
0.0001 |
| 0 to <3 |
0 |
|
0 |
|
|
|
| 3 to <6 |
8 |
2% |
9 |
2% |
|
|
| 6 to <9 |
48 |
11% |
60 |
13% |
|
|
| 9 to <12 |
39 |
9% |
46 |
10% |
|
|
| 12 to <18 |
87 |
20% |
118 |
26% |
|
|
| 18 to <24 |
102 |
23% |
106 |
24% |
|
|
| 24 to <36 |
160 |
36% |
112 |
25% |
|
|
| Gestational age (weeks) |
378 |
37.7 (2.8) |
426 |
38.1 (2.3) |
0.4 [0 to 0.7] |
0.04 |
| Birth weight (kg) |
431 |
2.97 (0.65) |
431 |
3.06 (0.61) |
0.09 [0.00 to 0.17] |
0.04 |
| Sex (female) |
210 |
47% |
230 |
51% |
4% [−3 to 10] |
0.27 |
|
General health | ||||||
| SKIN assessed |
434/444 |
98% |
435/451 |
96% |
|
|
| Normal |
326 |
75% |
303 |
70% |
−5% [−11 to 0] |
0.07 |
| Scabies |
19 |
4% |
53 |
12% |
8% [−4 to 11] |
<0.0001 |
| Impetigo |
62 |
14% |
67 |
15% |
1% [−4 to 6] |
0.64 |
| Tinea |
19 |
2% |
13 |
3% |
1% [−1 to 3] |
0.39 |
| other |
20 |
6% |
27 |
6% |
0% [−3 to 3] |
0.96 |
| Runny Nose |
165/432 |
38% |
198/445 |
44% |
6% [0 to 13] |
0.06 |
| Any cough |
86/436 |
20% |
169/457 |
38% |
18% [12 to 24] |
<0.0001 |
|
Other | ||||||
| Any antibiotics prescribed in previous 5 weeks |
130/444 |
29% |
189/451 |
42% |
12% [6 to 19] |
0.0001 |
| Beta-lactam |
101/444 |
23% |
158 |
35% |
12% [6-18] |
0.0001 |
| Macrolide |
14/444 |
3% |
18 |
4% |
1% [−2 to 3] |
0.50 |
| Topical |
18/426 |
4% |
18/433 |
4% |
0% [−3 to 3] |
0.97 |
| Haemoglobin (<11 mg/dL) | 122/402 | 30% | 139/403 | 34% | 4% [−2 to 11] | 0.21 |
*Bold signifies P value less than 0.05.