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. Author manuscript; available in PMC: 2014 Aug 29.
Published in final edited form as: J Carcinog Mutagen. 2013 Jul 29;1(Suppl 5):1–12. doi: 10.4172/2157-2518.S5-001

Figure 1. HNSCC mutations in histones and histone associated transcription regulators.

Figure 1

(A) Bar graph of 74 sequenced HNSCC tumor samples [121] containing mutations in epigenetic associated genes that encode histones and their linkers, proteins associated with the recruitment of DNA-binding proteins, HDAC I and II interacting proteins, corepressor proteins and transcriptional activators and coactivators. (B) Bar graph depicting the percentage of mutations found in HNSCC samples (n=74). (Graph generated from the analysis of the HNSCC NGS supporting data published by Stransky et. al. 2011.