Table 2.
Effect on cell proliferation from PGEs and free radical derivatives
| [Product] (µM) |
Cell Proliferation from the Treatment (% Viability at 48 h vs. Controla) | ||||
|---|---|---|---|---|---|
| PGE1 | PGE2 | 1-Hexanol | Heptanoic Acid | 8-OH-Octanoic Acid | |
| 0.01 | 108.6±3.3 | 108.5±4.3 | 89.8b±2.1 | 98.6±2.1 | 77.1c±5.1 |
| 0.1 | 109.5±2.7 | 112.7±2.9 | 87.7b±2.5 | 97.4±4.0 | 76.7c±5.3 |
| 1.0 | 106.2±3.5 | 116.9±5.4 | 90.2b±4.6 | 103.5±5.3 | 82.3c±6.2 |
At the range of 0.01 to 1.0 µM, PGE1, PGE2, 1-hexanol (derived from ●C6H13O), heptanoic acid (derived from ●C8H15O3), and 8-hydroxyoctanoid acid (derived from ●C7H13O2) were used to treat cells and tested for cell proliferation assay (MTS). Data represent the mean ± SD derived from three separate experiments with triplicate wells per condition.
a
% cell viability was compared with the control group (cells were incubated with 0.1 % ethanol);
b
significantly different (P < 0.01) vs. control; and
c
significantly different (P < 0.005) vs. control.