Table 4. Mouse PPIN topological properties of TF-targets vs NON-TF-targets.
Property | OCT4 vs NON-OCT4 | SOX2 vs NON-SOX2 | NANOG vs NON-NANOG | ||||||
Average | Average | P | Average | Average | P | Average | Average | P | |
ASPL | 4.922332 | 4.918182 | 0.8876 | 4.874096 | 4.946149 | 0.01026 | 4.882961 | 4.943273 | 0.03216 |
BC | 0.00119 | 0.000649 | 0.003523 | 0.0011367 | 0.0009639 | 0.4123 | 0.0013865 | 0.0008127 | 0.06287 |
Closeness | 0.2084117 | 0.2085047 | 0.9332 | 0.2101989 | 0.2075007 | 0.01171 | 0.2100418 | 0.2075065 | 0.0171 |
CC | 0.0942913 | 0.1020857 | 0.3649 | 0.0950919 | 0.0975313 | 0.7553 | 0.0964519 | 0.096816 | 0.9627 |
Degree | 4.076054 | 2.910638 | 1.95E-06 | 4.196402 | 3.463356 | 0.01287 | 4.364989 | 3.341736 | 0.00176 |
Eccentricity | 10.94014 | 10.8766 | 0.0646 | 10.9018 | 10.93072 | 0.3788 | 10.89157 | 10.9376 | 0.1595 |
NC | 41.7789 | 55.00762 | 4.25E-06 | 41.12322 | 48.35415 | 0.003487 | 41.62068 | 48.29418 | 0.006982 |
Radiality | 0.7548542 | 0.7551136 | 0.8876 | 0.757869 | 0.7533657 | 0.01026 | 0.7573149 | 0.7535454 | 0.03216 |
Stress | 118484.92 | 65591.25 | 0.002851 | 117399.72 | 94174.79 | 0.263 | 141375.3 | 79456.66 | 0.03827 |
TC | 0.1917032 | 0.1730731 | 0.02049 | 0.1852946 | 0.1863603 | 0.8874 | 0.1903151 | 0.1834669 | 0.3597 |