Figure 2.
KEGG molecular network of differentially expressed genes in iPSC-derived motor neurons of C9ALS patients and controls. When Entrez Gene IDs of 282 differentially expressed genes in iPSC-derived motor neurons of C9ALS patients and controls were imported into the Functional Annotation tool of DAVID, it identified “ECM-receptor interaction” (hsa04512) as the most relevant KEGG pathway. Light blue nodes indicate downregulated genes in C9ALS.