Figure 9.
Cells with spontaneous motility and without ECM degradation invade an ansitropic, aligned ECM environment. A: Morphology diagram of the invasion process for various values of parameters β and γ. Other parameters are kept constant (α = 1, λ = 1). Configurations shown were obtained at t=1,000 MCS (17 hours). B: Cell density changes along the direction of invasion reveals a steady invasion speed. Color-code indicates cell density compared to confluency. The temporal and spatial ranges represented on the vertical and horizontal axes are 2,000 MCS and 500 lattice units, respectively. Plots annotated as 1, 2 and 3 correspond to parameter values marked accordingly in panel A. Full time sequence is shown in Movie 4.