Table 4. Predictive factors of survival after bone metastases diagnosis.
| VARIABLES | MEDIAN TIME(MONTHS) | p VALUE(uni variate) | p VALUE(multivariate) | HAZARDRATIO (HR) |
| Age | 0.349 | |||
| <70 Years | 7.0 (5.83–8.18) | |||
| >70 Years | 6.0 (4.35–7.65) | |||
| Gender | 0.612 | |||
| Male | 6.0 (5.07–6.93) | |||
| Female | 9.0 (7.33–10.67) | |||
| Aetiology | 0.003 | 0.005 | 0.785 | |
| HBV-related | 4.0 (2.18–5.82) | |||
| HCV-related | 7.0 (5.61–8.39) | |||
| Alcohol-related cirrhosis | 9.0 (4.73–13.27) | |||
| Other | 8.0 (5.10–10.90) | |||
| Grading | 0.866 | |||
| G1 | 5.0 (3.38–6.62) | |||
| G2 | 6.0 (3.74–8.26) | |||
| G3 | 6.0 (4.04–7.96) | |||
| Locoregional Treatment | 0.104 | |||
| No | 6.0 (4.93–7.07) | |||
| Yes | 7.0 (5.97–8.03) | |||
| Type of locoregional Treatment | 0.644 | |||
| Surgery | 8.0 (6.23–9.77) | |||
| Interventional Radiology | 7.0 (5.72–8.28) | |||
| Type of interventional Radiology | 0.366 | |||
| RFA | 7.0 (4.76–9.24) | |||
| TACE | 7.0 (5.25–8.76) | |||
| PEI | 7.0 (0.00–19.47) | |||
| CHILD Score (at time of Bone Metastasis) | 0.245 | |||
| A | 6.0 (4.95–7.06) | |||
| B | 6.0 (3.93–8.07) | |||
| C | 9.0 (5.08–12.92) | |||
| AFP (at diagnosis) | 0.549 | |||
| <43 ng\ml | 7.0 (5.22–8.78) | |||
| >43 ng/ml | 7.0 (5.93–8.07) | |||
| Visceral Metastasis | 0.615 | |||
| Yes | 7.0 (4.14–9.86) | |||
| No | 7.0 (6.03–7.97) | |||
| ECOG PS (at time of Bone Metastasis) | 0.002 | 0.002 | 1.341 | |
| 0 | 8.0 (5.28–10.72) | |||
| 1 | 8.0 (6.75–9.25) | |||
| 2 | 6.0 (4.85–7.15) | |||
| 3 | 4.0 (0.33–7.67) | |||
| Bone Lesion Type | 0.608 | |||
| Osteolytic | 7.0 (6.05–7.95) | |||
| Ostroblastic | 9.0 (7.70–10.30) | |||
| Mixed | 7.0 (4.16–9.84) | |||
| Bone metastasis - Spine | 0.006 | 0.075 | 1.339 | |
| No | 9.0 (7.34–10.66) | |||
| Yes | 6.0 (5.05–6.95) | |||
| Bone Metastasis - Long Bones | 0.806 | |||
| No | 7.0 (6.11–7.89) | |||
| Yes | 6.0 (2.48–9.52) | |||
| Bone Metastasis - Hip | 0.428 | |||
| No | 7.0 (5.95–8.05) | |||
| Yes | 6.0 (3.65–8.35) | |||
| Bone Metastasis - Other | 0.941 | |||
| No | 7.0 (5.86–8.14) | |||
| Yes | 7.0 (5.60–8.40) | |||
| First SRE Type | 0.268 | |||
| Pathologica Fracture | 7.0 (3.90–10.10) | |||
| Hypercalcemia | 9.0 (7.83–10–17) | |||
| Spinal Cord Compression | 4.0 (0.00–9.09) | |||
| Surgery to Bone | 9.0 (7.83–10.17) | |||
| Radiation to Bone | 8.0 (6.55–9.45) | |||
| Biphosphonate Treatment | 0.001 | 0.024 | 0.699 | |
| No | 5.0 (3.58–6.42) | |||
| Yes | 8.0 (6.78–9.23) |