Table 5. Predictive factors of survival after HCC diagnosis.

VARIABLES	MEDIAN TIME[MONTHS (95% C.I.)]	p VALUE(univariate)	p VALUE(multivariate)	HAZARDRATIO (HR)
Age		0.818
<70 Years	18.0 (14.45–21.55)
>70 Years	20.0 (16.77–23.23)
Gender		0.589
Male	19.0 (14.06–23.94)
Female	19.0 (15.48–22.52)
Aetiology		0.077
HBV-related	15.0 (11.18–18.82)
HCV-related	24.0 (20.49–27.51)
Alcohol-related cirrhosis	16.0 (4.27–27.73)
Other	13.0 (9.00–17.01)
Grading		0.019	0.137	1.250
G1	27.0 (12.31–41.69)
G2	26.0 (22.50–29.50)
G3	12.0 (9.52–14.48)
Locoregional Treatment		0.000	0.000	0.265
No	8.0 (4.43–11.57)
Yes	24.0 (22.59–25.41)
Type of locoregional Treatment		0.594
Surgery	21.0 (16.36–25.64)
Interventional Radiology	24.0 (21.94–26.06)
Type of interventional Radiology		0.180
RFA	26.0 (17.03–34.97)
TACE	24.0 (20.62–27.38)
PEI	29.0 (12.37–45.63)
CHILD Score (at time of Bone Metastasis)		0.001	0.049	1.572
A	21.0 (15.75–26.25)
B	18.0 (14.91–21.10)
C	16.0 (14.06–17.95)
AFP (at diagnosis)		0.419
<43 ng\ml	18.0 (12.03–23.97)
>43 ng/ml	19.0 (14.36–23.64)
Visceral Metastasis		0.091
Yes	24.0 (19.85–28.15)
No	18.0 (15.29–20.71)
Bone metastasis - Spine		0.018	0.001	2.281
No	21.0 (16.87–25.13)
Yes	19.0 (15.26–22.74)
Bone Metastasis - Long Bones		0.639
No	19.0 (15.65–22.35)
Yes	21.0 (9.59–32.41)
Bone Metastasis - Hip		0.840
No	23.0 (20.29–25.71)
Yes	15.0 (11.87–18.13)
Bone Metastasis - Other		0.718
No	19.0 (15.21–22.79)
Yes	19.0 (11.00–27.00)
First SRE Type		0.742
Pathologica Fracture	21.0 (16.68–25.32)
Hypercalcemia	19.0 (11.3–26.70)
Spinal Cord Compression	24.0 (9.97–38.03)
Surgery to Bone	18.0 (0.00–38.53)
Radiation to Bone	18.0 (12.86–23.14)
Biphosphonate Treatment		0.529
No	18.0 (12.64–23.36)
Yes	19.0 (16.35–21.65)