Figure 4. Cellular ruthenium concentrations in R-825 treated S. pneumoniae and with ferrichrome (Fch) competition as determined by ICP-MS.

(A) Ruthenium contents in wild-type S. pneumoniae and in piuA- mutant as treated with 15 µM R-825. (B) Ruthenium contents in wild-type S. pneumoniae in the addition of increasing ferrichrome. Results are representative of the mean±SEM from three independent experiments (*p<0.01).