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. 2014 Aug 29;9(8):e106029. doi: 10.1371/journal.pone.0106029

Figure 1. Effect of obesity on contraction of mesenteric arteries to angiotensin II and norepinephrine.

Figure 1

A- Non-cumulative concentration–response curves to angiotensin II (ANG II) obtained in different segments of endothelium intact and endothelium denuded mesenteric arteries from control and monosodium glutamate (MSG)-induced obese rats. The curves were performed on a top of a submaximal tone (30 to 40% of the maximum response) induced by norepinephrine (NE). B- Cumulative concentration–response curves to NE in endothelium intact and endothelium denuded mesenteric arteries from control and monosodium glutamate-induced obese rats. Each point represents the mean ± SEM. *, P<0.05 vs. Control; #, P<0.05 vs. respective group in the absence of endothelium. N = 5–6/group.