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. 2014 Aug 29;9(8):e106022. doi: 10.1371/journal.pone.0106022

Figure 1. Fibrosis progression rate (FPR) according to age at infection (> or ≤21 years, median value) and PNPLA3 148M/M status in 247 patients with chronic hepatitis C.

Figure 1

Box plots indicate median value and interquatile ranges, whiskers the 5th and 95th centiles. p = 0.001 for faster FPR in PNPLA3 148M/M positive vs. negative patients with older age at infection (>21 years). *p<0.0001 vs. patients with same PNPLA3 148M/M status and younger age at infection (≤21 years).