Table 2. Effect of PNPLA3 148M/M on (log10) FPR in 247 CHC patients according to different thresholds of age at infection.
| PNPLA3 | p value | ||
| 148I/I or I/M | 148M/M | ||
| 15 years; 25th centile (±puberty) | |||
| Younger | −1.25±0.3 (51) | −1.19±0.3 (9) | ns |
| Older | −0.98±0.3 (175) | −0.78±0.3 (12) | 0.038 |
| 18 years; “adulthood” | |||
| Younger | −1.25±0.3 (70) | −1.19±0.3 (9) | ns |
| Older | −0.99±0.3 (156) | −0.78±0.3 (12) | 0.045 |
| 21 years; median | |||
| Younger | −1.14±0.3 (110) | −1.16±0.3 (13) | ns |
| Older | −0.95±0.3 (116) | −0.64±0.2 (8) | 0.001 |
| 27 years; 75th centile | |||
| Younger | −1.10±0.3 (157) | −1.11±0.3 (14) | ns |
| Older | −0.90±0.3 (69) | −0.67±0.2 (7) | 0.01 |
(): number of subjects; ns: not significant.