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. 2014 Aug 29;9(8):e106354. doi: 10.1371/journal.pone.0106354

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© 2014 Matsushita et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The middle ECG shows ventricular arrhythmias recorded from vehicle-treated Gα_q-TG mice. PVC was frequently observed. In contrast, the upper and lower ECGs recorded from an NTG and olmesartan-treated Gα_q-TG mouse showed P waves and QRS complexes with regular RR intervals without any arrhythmia, indicating a sinus rhythm. Mice at the age of 32 weeks were used.