Table 2. Lipid parameters and Renal Function: Baseline values and changes at week 48.
Mean Baseline Values | Mean Changes From Baseline (95% Confidence Interval) | ||||
DRV/r + RAL | DRV/r + TDF/FTC | DRV/r + RAL | DRV/r+ TDF/FTC | P-value | |
Total Cholesterol (mg/dL) | 159 | 149 | +23.3 (+14.5– +32.2) | +6.5 (−1.4– +14.4) | 0.003 |
LDL-Cholesterol (mg/dL) | 94 | 88 | +11.2 (+2.6– +19.8) | +3.3 (−4.6– +11.2) | 0.097 |
HDL-Cholesterol (mg/dL) | 40 | 34 | +4.8 (−1.1– +10.8) | +7.2 (+3.7– +10.7) | 0.796 |
Triglycerides(mg/dL) | 131 | 182 | +21.2 (−6.9– +49.2) | −38.1 (−113.6– +37.4) | 0.156 |
Total Cholesterol/HDL | 4.59 | 4.78 | −0.25 (−0.83– +0.34) | −0.71 (−1.12– +0.29) | 0.270 |
Estimated GFR by CKD-EPI formula(ml/min) | 104 | 110 | −4.4 (+3.2– −11.6) | −7.9 (−2.5– −13.7) | 0.44 |