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Groups of five mice (10 mice in total) were treated with 3×1010 vp of Ad/VNA-BoNTA (A) or Ad/VNA-control (B) on day 0 and bled two weeks later and then monthly for four months. The VNA concentrations (ng/ml) over time for individual mice are represented by the different symbols. Symbols within the shaded area represent VNA serum levels below detection.
