Table 1. Serum VNA-BoNTA levels following Ad/VNA-BoNTA administration via different routes.

Routea	Estimated serum VNA-BoNTA levels (nM)b					Average(nM)	Average(µg/ml)
	Mouse 1	Mouse 2	Mouse 3	Mouse 4	Mouse 5
iv	6000	30000	50000	10000	50000	29000	970
ip	0.015	4000	4000	0.03	1000	1800	60
im	ND	1000	1000	2000	800	960	32
sq	400	100	1000	200	40	350	12

ND- not determined.

^aRoutes by which Ad was administered; iv-intravenous, ip-intraperitoneal, im-intramuscular, sq-subcutaneous.

^bSerum was collected 4 days post-treatment and VNA levels estimated by dilution ELISA for binding to toxin targets.