Table 2.
Univariate analysis of the risk factors associated with community-associated (CA)-MRSA genotype nasal colonization in the STAR*ICU trial
| Risk factors | CA-MRSA N=30, n (%) |
HA-MRSA N=180, n (%) |
PR | 95% C.I. | P Value |
|---|---|---|---|---|---|
| Demographic data | |||||
| Age mean; median (range), years | 51; 48 (21–97) | 65; 66 (21–92) | 0.96 | 0.95–0.98 | <.001 |
| Female gender | 12 (40.0) | 75 (41.7) | 0.94 | 0.48–1.85 | .86 |
| Race | |||||
| White | 17 (56.7) | 133 (73.9) | 1.00 | ||
| Black | 12 (40.0) | 37 (20.5) | 2.16 | 1.11–4.20 | .02 |
| Other | 1 (3.3) | 10 (5.6) | 0.80 | 0.11–5.48 | .82 |
| Health care–associated risk factors | |||||
| Hospitalized in past year | 14 (46.7) | 134 (74.4) | 0.37 | 0.19–0.70 | .003 |
| Surgery in past year | 7 (23.3) | 70 (38.9) | 0.53 | 0.24–1.17 | .11 |
| Documented history of | |||||
| MRSA colonization | 4 (13.3) | 55 (30.6) | 0.39 | 0.14–1.08 | .07 |
| VRE colonization | 1 (3.3) | 24 (13.3) | 0.26 | 0.04–1.79 | .17 |
| MRSA or VRE colonization | 4 (13.3) | 66 (36.7) | 0.31 | 0.11–0.85 | .03 |
| Length of stay in hospital before ICU admission, mean, median (range), days | 4.2; 0 (0–70) | 3.5; 0 (0–49) | 1.01 | 0.97–1.05 | .66 |
| Device in place at ICU Admission | |||||
| Indwelling Device at ICU Admission | 15 (50.0) | 113 (62.8) | 0.64 | 0.33–1.24 | .19 |
| Gastrostomy Tube | 0 (0) | 15 (8.3) | undefined | undefined | 1.00 |
| Tracheostomy Tube | 3 (10.0) | 10 (5.6) | 1.68 | 0.59–4.82 | .33 |
| Indwelling Urinary Catheter | 12 (40.0) | 94 (52.2) | 0.65 | 0.33–1.29 | .22 |
| Central Venous Catheter | 5 (16.7) | 43 (23.9) | 0.68 | 0.27–1.67 | .39 |
| PICC | 1 (3.3) | 12 (6.7) | 0.52 | 0.08–3.54 | .51 |
| Medical history | |||||
| History of Solid Tumor | 4 (13.3) | 32 (17.8) | 0.74 | 0.28–2.00 | .56 |
| History of Hematologic Malignancy | 1 (3.3) | 6 (3.3) | 1.00 | 0.16–6.33 | 1.00 |
| History of Hematopoietic Stem Cell or Bone Marrow Transplant | 1 (3.3) | 2 (1.1) | 2.38 | 0.46–12.21 | .30 |
| History of Solid Organ Transplant | 2 (6.7) | 12 (6.7) | 1.00 | 0.27–3.77 | 1.00 |
| History of Chronic Hemodialysis | 1 (3.3) | 25 (13.9) | 0.24 | 0.03–1.72 | .16 |
| History of Chronic Hepatic Failure | 1 (3.3) | 16 (8.9) | 0.39 | 0.06–2.70 | .34 |
MRSA=methicillin-resistant Staphylococcus aureus
VRE=vancomycin-resistant Enterococcus
ICU=Intensive Care Unit
HA=healthcare-associated; CA=community-associated
PR=Prevalence Ratio
CI=Confidence Interval
PICC=peripherally inserted central catheter