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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Cell Tissue Res. 2014 May 24;357(3):815–821. doi: 10.1007/s00441-014-1900-2

Fig. 3.

Fig. 3

Muscle hypertrophy in old mice in ØY+T: O pairing is associated with stimulation of notch signaling. a, Western blots of muscle lysates show ØY+T: O but not ØY: O pairing fully restores Notch-1 expression to levels seen in young (Y) controls. Activation of Notch signaling in these heterochronic old parabionts is associated with increased expression of PCNA in muscle lysates. b and c, Quantification of band intensities. Values are mean ± SEM. Means with unlike superscripts are significantly (P<0.05) different.