Table 1.
Morphometric data on volumetric composition (Vv%) of normal looking mitochondria (NMIT), vacuolated mitochondria (VMIT), intramyofibrillar lipid (IML) accumulation, and tubular aggregation (TA) in skeletal muscles of young (Y), old (O), and O mice in various parabiotic pairings with untreated (Y:O), castrated (ØY:O), and castrated + 1cm testosterone-treated young males (ØY+T:O).
Treatment | NMIT | VMIT | IML | TA |
---|---|---|---|---|
Y | 5.55 ± 1.17A | 0.25 ± 0.05A | 0.17 ± 0.05A | 0A |
O | 1.73 ± 0.33B | 2.23 ± 0.33B | 2.32 ± 0.01B | 9.30 ± 2.14B |
Y: O | 4.40 ± 0.55A | 1.35 ± 0.29C | 1.23 ± 0.21C | 5.93 ± 0.55B |
ØY: O | 1.92 ± 0.16B | 2.81 ± 0.91B | 3.02 ± 0.85B | 18.45 ± 4.63C |
ØY+T: O | 10.86 ± 2.24C | 1.08 ± 0.07C | 0.69 ± 0.09D | 3.63 ± 0.44D |
Vv%, volume density expressed as a percentage of the myofibrillar volume. Values are given as mean ± SEM. In each column, means with unlike superscripts are significantly (P<0.05) different.