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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Bone. 2014 Jul 9;67:81–94. doi: 10.1016/j.bone.2014.06.040

Figure 4. Histology of P15 calvarial bones and sutures.

Figure 4

Histologic staining of non-decalcified sagittal sections of P15 Alpl+/+ (A) and Alpl−/− (E) mouse skulls are shown (black stains mineral). Red arrows point to lamdoid and coronal sutures. (B,F) 10x magnification of Alpl+/+ (B) and Alpl−/− (F) coronal suture and surrounding tissues. (C,G) 10× magnification of Alpl+/+ (C) and Alpl−/− (G) lambdoid suture and surrounding tissues. (D,H) 10x magnification of Alpl+/+ (D) and Alpl−/− (H) anterior frontal bone (red bracket shown in A,E). In addition to diminished mineralization, the Alpl−/− bone exhibit diminished marrow space. Red arrow points to marrow in Alpl+/+ and bone matrix in Alpl−/− mice.