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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Cell Tissue Res. 2014 Jun 15;357(3):549–561. doi: 10.1007/s00441-014-1925-6

Fig. 1.

Fig. 1

Prickle1 is expressed by the migrating FBMs as revealed by mRNA in situ hybridization. a: Prickle1 is highly expressed by the pre-migration FBMs at E10.5. In addition, Prickle1 expression is also detected in other motor neurons. b–f: Prickle1 is expressed by the FBMs from E11.5 to E13.5, and trigeminal neurons (arrows). d and f: The expression level in Prickle1C251X/C251X is reduced and the facial nucleus is barely visible. The FBM nucleus forms in r6 in the wild-type, but spans from r4 to r6 in the homozygotic mutant. Arrow: trigeminal neurons; r4–r6: rhombomere 4–6.The scale bar is 500µm