Figure 3.
a Histology and tubular injury grading of WT and HSF-KO kidney tissue. Panels A, B, C & D are representative of PAS stained sections of WT and KO mice kidneys subject to sham surgery (Panels A&B) or 45 minutes ischemia and 24 hour reperfusion (Panels C&D). Original images are 10 × and insert images are 40 ×. The graph is the tubular injury score of n=5 for each condition, blinded to the scorers. (No significant difference between WT and HSF-KO after I/R, p=0.3)
b Histology and medullary vascular congestion grading of WT and HSF-KO kidney tissue. Panels E, F, G & H are representative of H&E stained sections of WT and HSF-KO mice kidneys subject to sham surgery (Panels E&F) or 45 minutes ischemia and 24 hour reperfusion (Panels G&H). Images are 4×. The graph is the vascular congestion score of n=5 for each condition, blinded to the scorers. * represents p< 0.0007 between groups.