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Histology and medullary vascular congestion grading of HSF-KO kidney tissue. HSF-KO mice were treated with PC61 or vehicle and subjected to I/R. Panels A and B are representative of H&E stained sections of HSF-KO mice kidneys treated with vehicle (A) or PC61 (B) and subjected to 45 minutes ischemia and 24 hr reperfusion. Images are 4×. The graph is the vascular congestion score of n=3 for each condition, blinded to the scorers. * represents p< 0.009 between groups.
