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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Neurogastroenterol Motil. 2014 Jul 20;26(9):1285–1297. doi: 10.1111/nmo.12391

Table 4. Comparison of immunotherapy responders and non-responders.

Responders (n=17) Non-responders (n=6) p value
Demographics
Median age (range) at diagnosis 36 yrs (16-76) 53.5 yrs (20-72) 0.22
Clinical Features
Subacute onset 9 (53%) 1 (17%) 0.18
Personal/family Hx autoimmunity 10 (59%) 2 (33%) 0.34
Paraneoplastic AGID 3 (18%) 0 (0%) 0.54
Laboratory abnormalities
Antinuclear antibody 7 (41%) 3 (50%) 1.0
Neural specific autoantibody 12 (71%) 4 (67%) 1.0
Extra intestinal autonomic testing
Abnormalities 14 of 16 (88%) 5 of 5 (100%) 1.0
Post immunotherapy improvement 6 of 7 (86%) 1 of 3 (33%) 0.18
Immunotherapy Treatment
Median time from onset to immunotherapy 19 months (4-123) 71 months (5-201) 0.13
IVIg (in those with single agent utilized) 10 of 15 (67%) 5 of 5 (100%) 0.27

Abbreviations: AGID, autoimmune gastrointestinal dysmotility; Hx, history; IVIg, intravenous immune globulin; yrs, years.