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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Trends Biochem Sci. 2014 Aug 14;39(9):381–399. doi: 10.1016/j.tibs.2014.07.002

Figure 4. Timeline of genomic approaches for experimental and computational studies of TF-DNA binding specificity.

Figure 4

Development of experimental high-throughput DNA binding assays (above timeline axis) and computational DNA binding specificity models and algorithms (below timeline axis). Further examples of these experimental approaches and computational methods are provided in Table 1.