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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Pathol. 2014 Jul;233(3):228–237. doi: 10.1002/path.4353

Figure 1. mogp-TAg FT contains lesions (mSTICs) similar to human STICs.

Figure 1

H&E staining of a representative 7-8 week old mogp-TAg FT. The blue arrow points to the presence of a lesion, mSTIC, with abnormal chromatin, epithelial stratification, apoptotic bodies and nuclear enlargement, all characteristics of human STICs (human STIC shown in inset for comparison). Adjacent serial sections with immunohistochemical staining against TAg, p53, and Ki-67. All three markers exhibit intense and diffuse positive staining in the mSTIC area of the FT epithelium. Ki-67 and TAg are positive in the stromal area as well.